Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of pig brain POPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant porcine PREP expressed in Escherichia coli using Suc-Gly-Pro-AMC as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against prolyl oligopeptidase of porcine brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against prolyl oligopeptidase of porcine brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against prolyl oligopeptidase of porcine brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PREP in C57BL/6 mouse cortex homogenate assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-4-methylcoumarin as s...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibitory activity against prolyl oligopeptidase of porcine brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:In vitro inhibition of prolyl oligopeptidase (POP) from pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.325nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:In vitro inhibitory activity of the compound against prolyl oligopeptidase (POP) from pigbrain expressedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:In vitro inhibitory activity of the compound against prolyl oligopeptidase (POP) from pig brain ;value ranges from (1.1-2.2)More data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:In vitro inhibition of prolyl oligopeptidase (POP) from pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain.More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain.More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain.More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Compound was evaluated for the inhibition of prolyl endopeptidase (PEP) purified from human peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain.More data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain.More data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:In vitro inhibition of prolyl oligopeptidase (POP) from pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:In vitro inhibition of prolyl oligopeptidase (POP) from pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:In vitro inhibition of prolyl oligopeptidase (POP) from pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.730nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Inhibition of POP in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of POP in rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of pig brain POPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain.More data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:Inhibition of recombinant porcine brain PREP expressed in Escherichia coli assessed as formation of 7-amido-4-methylcoumarin using Suc-Gly-Pro-amido-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.870nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.870nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair